Serum tumour markers in malignant mesothelioma
نویسنده
چکیده
Malignant mesothelioma is a rare malignancy of the body cavities with dismal prognosis. It has been a diagnostic dilemma for years with many clinical and pathological mimics. Discovery of a reliable tumour marker will MESOTHELIN RELATED Pallavi Rao, Srikanth PEPTIDE Narayanaswamy Derriford Hospital, Plymouth, United Mesothelin is a glycophosphatidylinKingdom ositol anchored glycoprotein, which has function of cell to cell adhesion. For correspondence: definitely be of value in screening individuals with a history It is a marker of normal mesothelial Dr. Pallavi Rao, of asbestos exposure, diagnosis, treatment and follow up cells and is over expressed in 28, Catsketon Close, of malignant mesothelioma. Many tumour markers have malignant mesothelioma. However Plymouth PL3 5AE, been studied and speculatively associated with the what leads to the release of these Plymouth, malignant mesothelioma, but much still needs to be peptides from the cell surface to the United Kingdom. E-mail: blood stream is still under [email protected] speculation. Some suggest a mutation
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